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Morbidity for men and women with hypogonadism includes infertility and an increased risk of osteoporosis; there is no increase in mortality...., Developmental anomalies associated with the genital system (eg, hypospadias, micropenis, and cryptorchidism) [ 1 ]..., For postpubertal males, the rate of beard growth, libido and sexual function, muscle strength, and energy levels... Click to Read More
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Androgen insensitivity syndrome (AIS), formerly known as testicular feminization, is an X-linked recessive condition resulting in a failure of normal masculinization of the external genitalia in chromosomally male individuals. This failure of virilization..., Both individuals with partial androgen insensitivity syndrome and individuals with complete androgen insensitivity syndrome have 46,XY karyotypes. Individuals with complete androgen insensitivity syndrome have female external genitalia with normal labia,..., Penoscrotal hypospadias is shown. Note the associated ventral chordee and true urethral meatus located at the scrotal level.... Click to Read More
4). Anabolic Steroid Use and Abuse: Practice Essentials, Biopharmacology of Testosterone, Biochemistry and Pharmacology
Steroids are a general class of agents that all have the steroid ring in common. The steroid ring is composed of three 6-carbon rings and one 5-carbon ring joined, of which cholesterol is the most basic form and, indeed, the precursor. Although the term..., Testosterone is the principle hormone in humans that produces male secondary sex characteristics ( androgenic ) and is an important hormone in maintaining adequate nitrogen balance, thus aiding in tissue healing and the maintenance of muscle mass (anabolic)...., AASs are drugs derived from the modification of the Testosterone molecule in order to augment or limit certain characteristics of testosterone. In general, Testosterone has been altered to produce drugs that are more or less anabolic, are more or less... Click to Read More
Careful history taking, including of family and medication history, along with a physical examination, can guide the differential diagnosis and appropriate workup in hypogonadism. In postpubertal males, measurement of morning serum Testosterone concentrations..., LH and FSH can be used to distinguish between hypogonadotropic and hypergonadotropic hypogonadism and guide further evaluation and management in both males and females. Hypergonadotropic hypogonadism indicates a primary gonadal defect (congenital or acquired),..., Further hormonal testing (ie, measurement of serum prolactin or thyroid function tests) can be ordered based on presentation and history. Obtaining a karyotype can be considered in certain cases.... Click to Read More