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1). Pediatric Diabetic Ketoacidosis Emergency Department Care: Background, Pathophysiology, Epidemiology
Diabetic ketoacidosis (DKA) is a complex metabolic state of hyperglycemia, ketosis, and acidosis. [ 1 , 2 ] Diabetic ketoacidosis results from untreated absolute or relative deficiency of insulin in type 1 or type 2 diabetes mellitus , respectively...., Hyperglycemia results from impaired glucose uptake because of insulin deficiency and excess glucagon with resultant gluconeogenesis and glycogenolysis. Glucagon excess also increases lipolysis with the formation of ketoacids. Ketone bodies provide alternative..., Hyperglycemia causes an osmotic diuresis that leads to excessive loss of free water and electrolytes. Resultant hypovolemia leads to tissue hypoperfusion and lactic acidosis .... Click to Read More
Best Image and Ilustration about Paediatric Dka - Diabetic ketoacidosis in children and adolescents: An update and ....
Continuing Education in Anaesthesia Critical Care & Pain, Volume 9, Issue 6, 1 December 2009, Pages 194199, https://doi.org/10.1093/bjaceaccp/mkp034..., Simon Steel, Shane M. Tibby; Paediatric diabetic ketoacidosis, Continuing Education in Anaesthesia Critical Care & Pain, Volume 9, Issue 6, 1 December 2009, Pages 194199, https://doi.org/10.1093/bjaceaccp/mkp034..., Diabetic ketoacidosis (DKA) is the leading cause of morbidity and mortality in children with diabetes. Cerebral oedema is the most common cause of death and a high index of suspicion is always required.... Click to Read More
Specific high risk groups (ie. Teenagers, children on insulin pumps and those from lower socio-economic status)...., Remember that glucose should be consideredthe sixth vital sign and any sick appearingchild should have a point of care glucose done!..., Once Dka is suspected, elements on history should focus on screening for symptoms of diabetes (polyuria, polydipsia, enuresis ,weight loss) as well as symptoms of Dka (nausea, vomiting, abdominal pain, decreased alertness). However, be sure to take the... Click to Read More
1Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida USA..., The object of this review is to provide the definitions, frequency, risk factors, pathophysiology, diagnostic considerations, and management recommendations for diabetic ketoacidosis (DKA) in children and adolescents, and to convey current knowledge of..., Keywords: adolescents, cerebral edema, children, complications, diabetic ketoacidosis, fluid replacement, hypokalemia, management, prevention, recurrent DKA... Click to Read More
Division of Endocrinology and Metabolism, Children’s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario..., Correspondence and reprints: Dr Sarah E Lawrence, Division of Endocrinology and Metabolism, Children’s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario K1H 8L1. Telephone 613-737-7600 ext 2434, fax 613-738-4236, e-mail [email protected], Diabetic ketoacidosis (DKA) continues to be a common presentation of both type 1 and type 2 diabetes in children and adolescents. Early recognition and treatment in patients with new-onset diabetes are essential to the prevention of this potentially... Click to Read More